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Clinical trials
- Participate in a clinical trial
- For medical professionals
- Active clinical trials for pediatric cancers
- CAR-20/19-T cells in pediatric and young adult patients with relapsed/refractory B Cell Acute Lymphoblastic Leukemia (CAR-20/19-T) phase 1 clinical trial
- Unrelated and partially matched related donor peripheral stem cell transplantation for patients with hematologic malignancies clinical trial
- Early stage research
Active clinical trials
Cancer Clinical Trials - COG-ACNS1821
Protocol Summary
- Protocol No
- COG-ACNS1821
- Principal Investigator
- Sarah Rumler
- Phase
- I/II
- Title
- A Phase 1/2 Trial of Selinexor (KPT-330) and Radiation Therapy in Newly-Diagnosed Pediatric Diffuse Intrinsic Pontine Glioma (DIPG) and High-Grade Glioma (HGG)
- Associated Disease(s)
-
Brain and Spinal Cord Tumors
- Description (Summary)
- This study looks at how well selinexor works when given to children and young adults with HGG or DIPG. Selinexor is experimental because it has not been proven to work in a situation like yours.The overall goals of this study are to find the highest dose of selinexor that we can give safely with radiation therapy, and to find out what effects, good and/or bad, selinexor has on people with HGG, DMG or DIPG.
- Participating Institutions
- Childrens Hospital of Wisconsin
- ClinicalTrials.gov
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Why participate in clinical trials?
